Compound Index
NAD+ and Skeletal Muscle Research: Metabolism, Atrophy Prevention, and Protocol Design
A comprehensive research guide covering NAD+ mechanisms in skeletal muscle — SIRT1/SIRT3 substrate targets, NAMPT salvage pathway, muscle atrophy prevention (MuRF-1/Atrogin-1), mitochondrial biogenesis, glucose uptake, and published preclinical protocols for aging muscle research.
Epigenetic Aging Clocks: Horvath, GrimAge, and Peptide Research Applications
A comprehensive guide to epigenetic aging clocks (Horvath, Hannum, PhenoAge, GrimAge, DunedinPACE) and how longevity peptides — NAD+, Epitalon, GHK-Cu, SS-31, and MOTS-c — affect measurable CpG methylation and biological age endpoints in preclinical research.
MOTS-c: Mitochondria-Derived Peptide and Metabolic Research
A research-focused guide to MOTS-c — the mitochondrial-encoded peptide that activates AMPK, drives GLUT4 nuclear translocation, and acts as an exercise mimetic. Covers mechanism, Lee 2015 Cell Metabolism data, age-related decline, and preclinical dosing protocols.