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Nexphoria

Compound Tag

IGF-1

8 research articles in this compound library

GH Axis9 min read

IGF-1 in Peptide Research: Why It's the Key Biomarker

IGF-1 is the primary endpoint for GH axis peptide research. This guide covers IGF-1 biology (GHR/JAK2/STAT5b), normal reference ranges, published IGF-1 elevation data for all major GH secretagogues, sampling timing requirements, confounders (nutrition, sex, age, stress), ELISA selection guidance, and a full research design framework for using IGF-1 as your primary endpoint.

May 29, 2026Read
Research Fundamentals9 min read

Insulin-Like Growth Factor 1 (IGF-1) vs Growth Hormone: The Downstream Mediator Explained

A deep technical dive into the GH/IGF-1 axis: GHR/JAK2/STAT5b/IGF-1 hepatic synthesis, IGFBP-3 ternary complex, why IGF-1 is the standard proxy endpoint for GH secretagogue research, reference ranges by strain/sex/age, and critical confounders in endpoint design.

May 29, 2026Read
GH Axis10 min read

MK-677 vs Ipamorelin vs CJC-1295: Which GH Secretagogue for Your Research?

A comparative research guide to MK-677 (ibutamoren), ipamorelin, and CJC-1295 No DAC — covering mechanisms, published IGF-1 data, half-life differences, pulsatile vs continuous GH elevation, and a decision matrix for choosing the right compound for your study design.

May 29, 2026Read
Research Fundamentals10 min read

Complete Blood Panel Guide for Peptide Researchers

Which lab markers to track, when to sample, reference ranges by species and sex, and how to interpret CBC, CMP, hormone panels, and specialized biomarkers when running peptide research protocols.

May 29, 2026Read
Compound Profiles9 min read

MK-677 (Ibutamoren): The Researcher's Guide to Oral GH Secretagogues

A research-focused guide to MK-677 (ibutamoren) — GHSR-1a agonism, oral bioavailability versus injectable secretagogues, Nass 2008 IGF-1 data, lean mass studies, sleep architecture effects, dose-response in rodents, and research design tips for oral GH axis studies.

May 28, 2026Read
GH Axis10 min read

Sermorelin: GHRH Analog and Anti-Aging Research

A deep dive into sermorelin — the first 29 amino acids of GHRH, its pulsatile GH-stimulating mechanism, published RCT data on lean mass and bone density, and its role in anti-aging and GH axis research.

May 28, 2026Read
GH Axis10 min read

CJC-1295 + Ipamorelin: The GH Axis Stack Deep Dive

The most-studied GH secretagogue combination in peptide research — covering dual mechanism synergy, published IGF-1 and GH pulse data, ipamorelin's selectivity advantage, pulsatile vs continuous protocols, and research design considerations for the CJC-1295 No DAC + ipamorelin stack.

May 28, 2026Read
GH Axis10 min read

Ipamorelin Dosing, Timing, and Protocol Design: A Researcher's Reference

A comprehensive research reference for ipamorelin: GHSR-1a selectivity, published dose-response data from Johansen 1999 and Arvat 1997, pulsatile timing strategies, combination protocols with CJC-1295 No DAC and MK-677, and 6-month vs 3-month research cycle considerations.

May 28, 2026Read
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