Compound Tag
NMN / NR / NAD+ Precursors
4 research articles in this compound library
Compound Index
NAD+ Precursors in Research: NMN vs NR vs Direct NAD+ Injection
A pharmacological deep dive into the three main NAD+ replenishment strategies used in preclinical research — NMN, NR, and direct injectable NAD+. Covers intracellular conversion pathways, bioavailability differences, published rodent dose data, the Slc12a8 transporter controversy, methylation burden considerations, and which form to use for which research question.
NAD+ Research Protocols: Dosing, Routes, and Study Design
A practical research guide covering NAD+ and precursor dosing protocols — injectable vs oral vs IV forms, published rodent dose-response data, reconstitution protocol, light sensitivity, sirtuin activation endpoints, NAMPT inhibition controls, and four critical study design considerations.
Peptide Stacking for Longevity: NAD+, Epitalon, SS-31, and GHK-Cu
A mechanistic deep dive into the four-compound longevity research stack: NAD+ (sirtuin/mitochondrial biogenesis), Epitalon (telomerase/melatonin), SS-31 (cardiolipin/mitochondrial ETC), and GHK-Cu (Nrf2/collagen/gene expression). Covers synergy rationale, full factorial study design, endpoint selection, dosing protocols, and research design considerations.
NAD+: Cellular Energy, Sirtuins, and Longevity Research
A deep dive into NAD+ as a research compound — covering its role as a redox coenzyme, the NAMPT salvage pathway, sirtuin and PARP activation, mitochondrial biogenesis via PGC-1alpha, and a critical comparison of NR, NMN, and IV NAD+ in published research.