NEXPHORIA
MOTS-c
Mitochondria-derived peptide. Metabolic regulation and exercise mimetic research.
Purchase Type
Fresh cold-chain delivery every 30 days
Format
For Research Use Only — Not For Human Consumption
This compound is sold exclusively for qualified research purposes. Not approved by the FDA for therapeutic use.
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a 16-amino acid peptide encoded by the mitochondrial genome. Discovered in 2015 by Lee et al. at USC, it represents a new class of mitochondria-derived peptides (MDPs) that communicate between mitochondria and the nucleus. Circulating MOTS-c levels decline with age and correlate with metabolic health markers.
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Frequently Bought Together
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Researchers commonly order these compounds together. Convenient multi-compound ordering.
Anti-Aging
This itemMOTS-c
10mg
$144
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Research Journal
Related Research Articles
NAD+ and Skeletal Muscle Research: Metabolism, Atrophy Prevention, and Protocol Design
A comprehensive research guide covering NAD+ mechanisms in skeletal muscle — SIRT1/SIRT3 substrate targets, NAMPT salvage pathway, muscle atrophy prevention (MuRF-1/Atrogin-1), mitochondrial biogenesis, glucose uptake, and published preclinical protocols for aging muscle research.
MOTS-c: Mitochondria-Derived Peptide and Metabolic Research
A research-focused guide to MOTS-c — the mitochondrial-encoded peptide that activates AMPK, drives GLUT4 nuclear translocation, and acts as an exercise mimetic. Covers mechanism, Lee 2015 Cell Metabolism data, age-related decline, and preclinical dosing protocols.
Epigenetic Aging Clocks: Horvath, GrimAge, and Peptide Research Applications
A comprehensive guide to epigenetic aging clocks (Horvath, Hannum, PhenoAge, GrimAge, DunedinPACE) and how longevity peptides — NAD+, Epitalon, GHK-Cu, SS-31, and MOTS-c — affect measurable CpG methylation and biological age endpoints in preclinical research.
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Mitochondrial Protocol
MOTS-c activates AMPK and mimics exercise-signaling; paired with NAD+ to support mitochondrial biogenesis across complementary pathways.
Anti-Aging
MOTS-c
10mg
$144
Wellness
NAD+
100mg
$30