Compound Index
Peptide Research for Metabolic Syndrome: Insulin Resistance, Hypertension, and Dyslipidemia Protocols
A comprehensive research guide to metabolic syndrome biology and multi-compound peptide protocols: GLP-1 agonist data from STEP 1 and SELECT, MOTS-c AMPK/ACC mechanism, AOD-9604 β3-AR lipolysis, and NAD+/SIRT1 lipogenesis suppression — with 5-component endpoint battery, 8-group study design, and reconstitution/storage guidance.
GLP-1 Agonists and Appetite Regulation: Hypothalamic Circuits, Ghrelin, and Hunger Endpoint Study Design
A mechanistic deep dive into how GLP-1 agonists suppress appetite through hypothalamic ARC/VMH circuits, ghrelin/GLP-1 axis interplay, gastric emptying, and reward pathway modulation — with validated hunger endpoints and study design for preclinical metabolic research.
Tirzepatide Lean Mass Preservation: GIPR, Body Composition, and Study Design
Why tirzepatide preserves lean mass better than semaglutide — GIPR adipose mechanism, SURMOUNT-1 body composition data, DIO rodent protocols, EchoMRI/DXA endpoints, and pair-fed study design.